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當(dāng)前位置:上海易佰聚經(jīng)貿(mào)有限公司>>品牌產(chǎn)品>>Peprotech細(xì)胞因子>> 210-13-2Recombinant Human IL-13
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產(chǎn)品型號(hào)210-13-2
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更新時(shí)間:2024-05-24 11:22:32瀏覽次數(shù):894次
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Recombinant Murine IL-13:
Description: IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Recombinant murine IL-13 is a 12.3 kDa protein consisting of 111 amino acid residues.
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