目錄:MedChemExpress LLC>>生化試劑>> Niacin hydrochloride | MCE
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CAS | 636-79-3 | 分子量 | 159.57 |
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分子式 | C?H?ClNO? | 供貨周期 | 現(xiàn)貨 |
貨號(hào) | HY-B0143A | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
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CAS No. : 636-79-3
產(chǎn)品活性:Niacin (Vitamin B3; Nicotinic acid) hydrochloride is an orally active B3 vitamin that is an essential nutrient for humans. Niacin hydrochloride plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin hydrochloride is also used in the study of cardiovascular diseases.
研究領(lǐng)域:Metabolic Enzyme/Protease | Apoptosis
作用靶點(diǎn):Endogenous Metabolite | Apoptosis
In Vitro: Niacin hydrochloride (0-900 μM, 42 hours) significantly increases GSH levels and decreases ROS levels, and affects the expression of genes related to apoptosis and lipid metabolism.
Niacin hydrochloride (0-40 μM, 24 hours) can inhibit cancer invasive activity at low dose but with no influence on proliferation.
In Vivo: Niacin hydrochloride (subcutaneous injection, 3-300 mg/kg, once) can induce vasodilation in a dose-dependent manner within minutes in male C57BL/6 mice.
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