技術(shù)文章
BIOMOMENTUM力學(xué)試驗機---在36個豬皮上的壓痕映射
閱讀:518 發(fā)布時間:2021-3-16BIOMOMENTUM力學(xué)試驗機---全厚度切割模型在36個豬皮上的壓痕映射
INDENTATION MAPPING ON 36 PIG SKINS FOR A FULL THICKNESS EXCISION MODEL
A world-wide renowned Pharma needed to mechanically characterize the healing of skin in a model of full thickness excision. To address their needs, we designed a study to perform the mechanical characterization of the samples the client sent to us. This characterization used two test configurations, namely indentation mapping and tensile testing.
Indentation mapping is a non-destructive technique in which automated indentation is performed throughout the surface of the sample. This technique has several advantages: it is non-destructive and allows the same sample to be used for other tests (e.g. tensile testing in this case) or characterization (e.g. histology). From the recording of each indentation, several mechanical properties can be obtained including the thickness, the structural stiffness and the instantaneous shear modulus. Combined with the positional information of each recording, the topography of the skin can be obtained and distinctive maps for each mechanical properties can be calculated. For this pilot study, maps for the thickness, structural stiffness and the instantaneous shear modulus were generated. From these maps, the area of the “wound” or the “affected skin” were assessed.
Due to the non-invasive nature of the indentation, the second approach used in this study was to perform tensile testing on the same sample to determine the load at rupture.
BIOMOMENTUM力學(xué)試驗機 需要以全厚度切除模型對皮膚的愈合進(jìn)行機械表征。為了滿足他們的需求,我們設(shè)計了一項研究,對客戶發(fā)送給我們的樣品進(jìn)行機械表征。此表征使用兩種測試配置,即壓痕映射和拉伸測試。
壓痕映射是一種非破壞性技術(shù),其中在整個樣品表面執(zhí)行自動壓痕。該技術(shù)具有幾個優(yōu)點:它是非破壞性的,并且可以將同一樣品用于其他測試(例如,在這種情況下為拉伸測試)或表征(例如,組織學(xué))。從每個壓痕的記錄中,可以獲得幾種機械性能,包括厚度,結(jié)構(gòu)剛度和瞬時剪切模量。結(jié)合每個記錄的位置信息,可以獲得皮膚的地形,并可以計算出每種機械性能的*圖。對于該初步研究,生成了厚度,結(jié)構(gòu)剛度和瞬時剪切模量的圖。從這些地圖中
biomomentum多軸機械測試儀Mach-1測試意義及適用范圍:
材料力學(xué)性能可以應(yīng)用到生產(chǎn)的任何階段,從測試原材料質(zhì)量直到檢查制成品的耐用性。 測試可對廣泛多樣的生物樣品、材料和產(chǎn)品進(jìn)行,包括軟組織、軟骨組織、皮膚組織、凝膠組織、高分子材料、生物產(chǎn)品、醫(yī)學(xué)鑒定和水凝膠等。力學(xué)性能測試可幫助企業(yè)向客戶證明其產(chǎn)品的力學(xué)性能、穩(wěn)定性和安性,從而獲得基礎(chǔ)數(shù)據(jù)和競爭勢。
1、多功能、多軸向,適用樣品范圍廣:
1.1、從骨等硬組織材料到腦組織、眼角膜等極軟的組織材料
1.2、從粗的椎間盤的樣品到極細(xì)的單纖維絲
2、力學(xué)類型測試分析功能齊全:
2.1、模塊化集成壓縮、張力、剪切、摩擦、扭轉(zhuǎn)、穿刺、摩擦和非平面壓痕、3D厚度、3D表面輪廓等各種力學(xué)類型支持,微觀結(jié)構(gòu)表征及動態(tài)力學(xué)分析研究
2.2、多物理場耦合加載測試
Mach-1多軸機械測試儀是模塊化集成壓縮,拉伸,剪切,摩擦,扭轉(zhuǎn)和3D壓痕映射、電位分布等測試設(shè)備
biomomentum至1999年以來,專注用于測試生物材料,組織和關(guān)節(jié)軟骨機-電特性產(chǎn)品的設(shè)計、開發(fā)、制造和商業(yè)化的創(chuàng)新解決方案20余年。
其mach-1多軸向多功能組織材料機械特性測試分析系統(tǒng)已經(jīng)成為組織材料機械-電位測試分析的黃金標(biāo)準(zhǔn)。
1、多功能、多軸向,適用樣品范圍廣:
•1.1、從骨等硬組織材料到腦組織、眼角膜等極軟的組織材料
•1.2、從粗的椎間盤的樣品到極細(xì)的單纖維絲
2、力學(xué)類型測試分析功能齊全:
2.1、模塊化集成壓縮、張力、剪切、摩擦、扭轉(zhuǎn)、穿刺、摩擦和非平面壓痕、3D厚度、3D表面輪廓等各種力學(xué)類型支持,微觀結(jié)構(gòu)表征及動態(tài)力學(xué)分析研究
2.2、多物理場耦合加載測試
•3、通高量壓痕、壓縮測試分析(48孔板中壓痕測試分析)
•4、高精度、高分辨率:
•4.1、位移分辨率達(dá)0.1um
•4.2、力分辨率達(dá)0.025mN
•4.3、樣品直徑小25um
•5、行程范圍廣:50-250mm
•6、體積小巧、可放入培養(yǎng)箱內(nèi)
•7 、DIC (Digital Image Correlation)數(shù)字圖像相關(guān)法非接觸式的高精度位移、應(yīng)變測量
•9、活性組織電位分布測試分析
•10、產(chǎn)品成熟,文獻(xiàn)量達(dá)上千篇