1565798-78-8，ACI，DOTA系列螯合劑，1,4,7,10-四氮雜環(huán)十二烷-1,4,7,10-四乙酸（DOTA）是一種大環(huán)絡(luò)合劑。通過螯合64銅放射性同位素，它已被用于碳納米管生物結(jié)合物的放射性標(biāo)記。在臨床放射中，DOTA可被N-羥基磺基琥珀酰亞胺激活，與單克隆結(jié)合。

1565798-78-8，ACI，DOTA系列螯合劑1,4,7,10-四氮雜環(huán)十二烷-1,4,7,10-四乙酸（DOTA）是一種大環(huán)絡(luò)合劑。通過螯合64銅放射性同位素，它已被用于碳納米管生物結(jié)合物的放射性標(biāo)記。在臨床放射中，DOTA可被N-羥基磺基琥珀酰亞胺激活，與單克隆結(jié)合。

名稱：ACI

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid

10-[2-[[3-[(2-Methyl-1-oxo-2-propen-1-yl)amino]propyl]amino]-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

CAS：1565798-78-8

化學(xué)式：C23H40N6O8

分子量：528.2908

結(jié)構(gòu)式以及核磁圖譜：

LCMS分析報(bào)告：

1565798-78-8，ACI，DOTA系列螯合劑產(chǎn)品簡介：1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) is a macrocyclic complexing agent. It has been used for radiolabeling of carbon nanotube bioconjugates by chelating 64 Cu radioisotope. DOTA can be activated with N -hydroxysulfosuccinimidyl for conjugation with monoclonal antibodies in clinical radioimmunotherapy.

相關(guān)化合物：

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid

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gadolinium(III) 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

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1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, triMethyl ester

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10-phosphonomethyl-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

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1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Tri-tert-butyl Ester

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1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Tri-tert-butyl Ester

18271-97-1

10-(3,6,9-trioxatridecyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

686289-85-0

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 1,4,7-tris(phenylmethyl) ester

957130-00-6