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Source

Rabbit

Applications

WB,IF,ELISA

Reactivity

Human,Mouse,Rat

Dilution

WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

Aldolase A Polyclonal Antibody detects endogenous levels of Aldolase A protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human ALDOA. AA range:1-50

Uniprot No

P04075

Alternative names

ALDOA; ALDA; Fructose-bisphosphate aldolase A; Lung cancer antigen NY-LU-1; Muscle-type aldolase

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

aldolase, fructose-bisphosphate A(ALDOA) Homo sapiens The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011],

Other

ALDOA, Fructose-bisphosphate aldolase A

Mol.Wt (Da)

39420

Concentration

1 mg/ml