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隱孢子蟲(chóng)Cryptosporidium快速檢測(cè)試劑盒??
廣州健侖生物科技有限公司
Cellabs公司是一個(gè)的生物技術(shù)公司，總部位于澳大利亞悉尼。專(zhuān)門(mén)研發(fā)與生產(chǎn)針對(duì)熱帶傳染性疾病的免疫診斷試劑盒。其產(chǎn)品40多個(gè)國(guó)家和地區(qū)。1998年，Cellabs收購(gòu)TropBio公司，進(jìn)一步鞏固其在研制熱帶傳染病、寄生蟲(chóng)診斷試劑方面的位置。
隱孢子蟲(chóng)Cryptosporidium快速檢測(cè)試劑盒
該公司的Crypto/Giardia Cel IFA是國(guó)標(biāo)*推薦的兩蟲(chóng)檢測(cè)IFA染色試劑、Crypto Cel Antibody Reagent是UK DWI水質(zhì)安全評(píng)估檢測(cè)的*抗體。
【Cellabs公司中國(guó)總代理】
Cellabs公司中國(guó)代理商廣州健侖生物科技有限公司自2014年就開(kāi)始與Cellabs公司攜手達(dá)成戰(zhàn)略合作伙伴，熱烈慶祝廣州健侖生物科技有限公司成為Cellabs公司中國(guó)總代理商。
我司為悉尼Cellabs公司在華代理商，負(fù)責(zé)Cellabs產(chǎn)品在中國(guó)的銷(xiāo)售及售后服務(wù)工作，詳情可以我司公司人員。
主要產(chǎn)品包括：隱孢子蟲(chóng)診斷試劑，賈第蟲(chóng)診斷試劑，瘧疾診斷試劑，衣原體檢測(cè)試劑，絲蟲(chóng)診斷試劑，錐蟲(chóng)診斷試劑等。
廣州健侖生物科技有限公司與cellabs達(dá)成代理協(xié)議，歡迎廣大用戶咨詢(xún)訂購(gòu)。
我司還提供其它進(jìn)口或國(guó)產(chǎn)試劑盒：登革熱、瘧疾、流感、A鏈球菌、合胞病毒、腮病毒、乙腦、寨卡、黃熱病、基孔肯雅熱、克錐蟲(chóng)病、違禁品濫用、肺炎球菌、軍團(tuán)菌、化妝品檢測(cè)、食品安全檢測(cè)等試劑盒以及日本生研細(xì)菌分型診斷血清、德國(guó)SiFin診斷血清、丹麥SSI診斷血清等產(chǎn)品。
歡迎咨詢(xún)
歡迎咨詢(xún)2042552662
【Cellabs公司產(chǎn)品介紹】
公司的主要產(chǎn)品有：隱孢子蟲(chóng)診斷試劑，賈第蟲(chóng)診斷試劑，瘧疾診斷試劑，衣原體檢測(cè)試劑，絲蟲(chóng)診斷試劑，錐蟲(chóng)診斷試劑等。Cellabs 的瘧疾ELISA試劑盒成為臨床上的一個(gè)重要的診斷工具盒科研上的重要鑒定工具。其瘧疾抗原HRP-2 ELISA檢測(cè)試劑盒和瘧疾抗體ELISA檢測(cè)試劑盒已經(jīng)成為醫(yī)學(xué)研究所的*試劑盒。Cellabs產(chǎn)品主要包括以下幾種方法學(xué)：直接（DFA）和間接（IFA）免疫熒光法，酶聯(lián)免疫吸附試驗(yàn)（ELISA），和膠體金快速測(cè)試。所有產(chǎn)品都是按照GMP、CE標(biāo)志按照ISO13485。
二維碼掃一掃
【公司名稱(chēng)】 廣州健侖生物科技有限公司
【】 楊永漢
【】
【騰訊 】 2042552662
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號(hào)二期2幢101-3室
【企業(yè)文化】
本蟲(chóng)主要寄生于小腸上皮細(xì)胞的刷狀緣納蟲(chóng)空泡內(nèi)。空腸近端是蟲(chóng)體寄生數(shù)量zui多的部位，嚴(yán)重者可擴(kuò)散到整個(gè)消化道。亦可寄生在呼吸道、肺臟、扁桃體、胰腺、膽囊和膽管等器官。
寄生于腸粘膜的蟲(chóng)體，使粘膜表面出現(xiàn)凹陷，或呈火山口狀。寄生數(shù)量多時(shí)，可導(dǎo)致廣泛的腸上皮細(xì)胞的絨毛萎縮、變短、變粗、或融合、移位和脫落，上皮細(xì)胞老化和脫落速度加快。固有層多形核白細(xì)胞、淋巴細(xì)胞和漿細(xì)胞浸潤(rùn)。此外，艾滋病患者并發(fā)隱孢子蟲(chóng)性膽囊炎、膽管炎時(shí)，除呈急性炎癥改變外，尚可引起壞疽樣壞死。
隱孢子蟲(chóng)的致病機(jī)理尚未*澄清，很可能與多種因素有關(guān)。小腸粘膜的廣泛受損，腸粘膜表面積減少，破壞了腸道吸收功能，特
電鏡圖片下的隱孢子蟲(chóng)
電鏡圖片下的隱孢子蟲(chóng)
別是脂肪和糖類(lèi)吸收功能?chē)?yán)重障礙，導(dǎo)致患者嚴(yán)重持久的腹瀉，大量水及電解質(zhì)從腸道丟失。
此外，由于隱孢子蟲(chóng)感染縮小了腸粘膜表面積，使得多種粘膜酶明顯減少，例如乳糖酶，這也是引起腹瀉的原因之一。
臨床癥狀的嚴(yán)重程度與病程長(zhǎng)短亦取決于宿主的免疫功能狀況。免疫功能正常宿主的癥狀一般較輕，潛伏期一般為3~8天，急性起病，腹瀉為主要癥狀，大便呈水樣或糊狀，一般無(wú)膿血，日排便2~20余次。嚴(yán)重感染的幼兒可出現(xiàn)噴射性水樣便，量多。常伴有痙攣性腹痛、腹脹、惡心、嘔吐、食欲減退或厭食、口渴和發(fā)熱。病程多為自限性，持續(xù)7~14天，但癥狀消失后數(shù)周，糞便中仍可帶有卵囊。少數(shù)病人遷延1~2個(gè)月或轉(zhuǎn)為慢性反復(fù)發(fā)作。免疫缺陷宿主的癥狀重，常為持續(xù)性霍亂樣水瀉，每日腹瀉數(shù)次至數(shù)十次，量多，達(dá)數(shù)升至數(shù)十升。常伴劇烈腹痛，水、電解質(zhì)紊亂和酸中毒。病程可遷延數(shù)月至1年。病人常并發(fā)腸外器官隱孢子蟲(chóng)病，如呼吸道和膽道感染，使得病情更為嚴(yán)重復(fù)雜。隱孢子蟲(chóng)感染常為AIDS病人并發(fā)腹瀉而死亡的原因。糞便（水樣或糊狀便為好）直接涂片染色，檢出卵囊即可確診。有時(shí)嘔吐物和痰也可作為受檢標(biāo)本。檢查方法有：（1）金胺—酚染色法：新鮮或甲醛固定后的標(biāo)本均可用此法，染色后在熒光顯微鏡下觀察。卵囊圓形呈明亮乳白—黃綠色熒光。低倍鏡下為圓形小亮點(diǎn)，周邊光滑，蟲(chóng)體數(shù)量多時(shí)可遍布視野，猶如夜空中繁星。高倍鏡下卵囊壁薄，中央淡染，似環(huán)狀。本法簡(jiǎn)便、敏感，適用于批量標(biāo)本的過(guò)篩檢查。
The worm mainly resides in the vacuole of the brush border worms of the small intestine epithelial cells. The proximal part of the jejunum is the site with the largest number of parasitic parasites, and severe cases can spread throughout the digestive tract. Can also parasite in the respiratory tract, lungs, tonsils, pancreas, gallbladder and bile duct and other organs.
Parasites that infest the intestinal mucosa make the surface of the mucosa appear concave or crater-like. When the amount of parasitism is large, the villus of the intestinal epithelial cells can be extensively atrophied, shortened, thickened, or fused, dislodged and dislodged, and the epithelial cells can be aged and shed faster. Intrinsic layer of polymorphonuclear leukocytes, lymphocytes and plasma cell infiltration. In addition, AIDS patients with cryptosporidiosis cholecystitis, cholangitis, in addition to acute inflammatory changes, can still cause gangrene necrosis.
The pathogenic mechanism of Cryptosporidium has not been compley clarified and it is likely to be related to a variety of factors. Extensive damage to the small intestine mucosa, reduced surface area of ??the intestinal mucosa, disrupted intestinal absorption, especially
Cryptosporidium under electron microscope pictures
Cryptosporidium under electron microscope pictures
It is not a serious obstacle to the absorption of fat and carbohydrates, leading to severe and persistent diarrhea in the patient, and a large amount of water and electrolytes lost from the intestine.
In addition, since Cryptosporidium infection reduces the surface area of ??the intestinal mucosa, a variety of mucosal enzymes are significantly reduced, such as lactase, which is one of the causes of diarrhea.
The severity of the clinical symptoms and the length of the disease also depend on the host's immune function status. Normal immune function of the host's symptoms are generally mild, the incubation period is generally 3 to 8 days, acute onset, diarrhea is the main symptom, the stool was watery or paste, generally no pus, daily defecation 2 to 20 times. Children who have serious infections may have jetty watery stools and have a large amount. Often accompanied by spastic abdominal pain, bloating, nausea, vomiting, loss of appetite or anorexia, thirst, and fever. The course of the disease is mostly self-limited for 7 to 14 days. However, the oocysts may still be present in the feces after the symptoms have disappeared. A small number of patients were postponed for 1 to 2 months or switched to chronic recurrent attacks. The symptoms of immune-deficient hosts are heavy, often persistent cholera-like watery diarrhea, with daily diarrhea several to dozens of times, and in large quantities up to several tens of liters. Often accompanied by severe abdominal pain, water, electrolyte imbalance and acidosis. The course of the disease can last for months to 1 year. Patients often have extra-intestinal organ cryptosporidiosis, such as respiratory and biliary tract infections, making the condition more serious and complex. Cryptosporidium infection is often the cause of death from diarrhea in AIDS patients. Faecal (water or paste is good) direct smear staining, detection of oocysts can be confirmed. Sometimes vomitus and sputum can also be used as specimens. Inspection methods are: (1) auramine-phenol staining method: fresh or formaldehyde-fixed specimens can be used in this method, stained and observed under a fluorescence microscope. The oocysts are round and bright white-yellow-green fluorescence. Under the low magnification lens, it has a round bright spot, smooth periphery, and a large number of insects can cover the field of vision for a long time, just like the stars in the night sky. Under high magnification, the oocysts are thin, lightly stained in the center, and resemble a ring. This method is simple, sensitive and suitable for screening inspections of bulk samples.
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