詳細(xì)介紹
HbsAg 乙肝表面抗原(鼠單克隆抗體)
廣州健侖生物科技有限公司
此抗體與乙肝病毒表面抗原的ad/ay亞型反應(yīng),在感染組織的細(xì)胞漿中呈現(xiàn)彌漫性著色,主要用于研究乙肝病毒表面抗原感染的組織,也可用于肝硬化、肝癌與乙肝病毒感染的相關(guān)性等方面研究。
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HbsAg 乙肝表面抗原(鼠單克隆抗體)
【產(chǎn)品介紹】
細(xì)胞定位:細(xì)胞核
適用組織:石蠟/冰凍
陽性對照:乙肝病毒感染組織
抗原修復(fù):熱修復(fù)(EDTA)
抗體孵育時間:60min
產(chǎn)品編號 | 抗體名稱 | 克隆型別 |
OB124 | GSTπ(胎盤型谷胱甘肽-S-轉(zhuǎn)移酶) | LW29 |
OB125 | HbcAg(乙肝核心抗原) | polyclonal |
OB126 | HbsAg(乙肝表面抗原) | S1-210 |
OB127 | hCG(絨毛膜促性腺激素) | polyclonal |
OB128 | Helicobacter pylori(幽門螺旋桿菌) | polyclonal |
OB129 | Hemoglobin A(血紅蛋白 A) | EPR3608 |
OB130 | hENT1 (人平衡型核苷轉(zhuǎn)運(yùn)蛋白1) | SP120 |
OB131 | Her2(細(xì)胞表面生長因子受體2) | EP3 |
OB132 | Her2(細(xì)胞表面生長因子受體2) | SP3 |
OB133 | HLA-Dra(人類白細(xì)胞抗原2) | LN-3 |
OB134 | HPV(人乳頭狀瘤病毒) | K1H8 |
OB135 | HSA(肝細(xì)胞特異性抗原)或Hepatocyte Specific Antigen或Hep Par-1 | OCH1E5 |
OB136 | IgA(免疫球蛋白A) | polyclonal |
OB137 | IgD(免疫球蛋白D) | polyclonal |
OB138 | IgG(免疫球蛋白G) | polyclonal |
OB139 | IgG4(免疫球蛋白G4) | MRQ-44 |
OB140 | IgM(免疫球蛋白M) | polyclonal |
HbsAg
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【公司名稱】 廣州健侖生物科技有限公司
【市場部】 歐
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【騰訊 】
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號二期2幢101-103室
這項研究意味著人們可以開發(fā)出精確的基因療法來預(yù)防和治療疾病,是高度個性化醫(yī)療的曙光。個性化醫(yī)療是非常重要的,因為人的個體差異對疾病發(fā)展影響很大。
CRISPR/Cas9是時下zui熱門的基因編輯系統(tǒng),Cas9蛋白可以說是基因工程的瑞士抗原抗體,可以結(jié)合并切割任意DNA。Church等人以一種新方式使用Cas9,讓它激活特定基因的轉(zhuǎn)錄,從而表達(dá)或抑制特定的遺傳學(xué)性狀。他們把Cas9與延長了三倍的轉(zhuǎn)錄因子融合起來,使其能夠強(qiáng)力控制單個或多個基因的表達(dá)。
“在基因工程領(lǐng)域,能控制遺傳學(xué)性狀的旋鈕越多越好,”Church說。“我們展示了一類全新的旋鈕,它們可以控制多個基因,決定特定遺傳學(xué)性狀的表達(dá)或表達(dá)程度?,F(xiàn)在我們可以極為精確的上調(diào)或下調(diào)基因表達(dá)。”研究人員在體外培養(yǎng)的酵母、果蠅、小鼠和人類細(xì)胞中證實(shí)了這一技術(shù)操縱基因表達(dá)的能力。
人類基因組90%的區(qū)域并不翻譯成蛋白質(zhì),曾經(jīng)被認(rèn)為是無用的垃圾。后來人們發(fā)現(xiàn),這一區(qū)域的基因以一種神秘的方式起作用,而且這些基因往往串聯(lián)起來發(fā)揮作用。Church等人開發(fā)的新方法,可以靶標(biāo)和激活這些人們知之甚少的DNA暗物質(zhì)。
This research means that people can develop precise gene therapy to prevent and cure diseases, which is the dawn of highly personalized medicine. Personalized medical care is very important, because individual differences in human beings have a great impact on disease development.
CRISPR / Cas9 is the hottest gene editing system of the moment. Cas9 protein is a genetically engineered Swiss antigen antibody that binds and cleaves any DNA. Church et al. Use Cas9 in a new way to activate the transcription of specific genes to express or suppress specific genetic traits. They fused Cas9 with a threefold-longer transcription factor, enabling them to aggressively control the expression of single or multiple genes.
"In genetic engineering, the more knobs that control genetic traits, the better," Church said. "We showed a new class of knobs that control multiple genes and determine the level of expression or expression of specific genetic traits, and we can now very accuray up-regulate or down-regulate them." The researchers studied in vitro yeast The ability of the technique to manipulate gene expression is confirmed in flies, mice and human cells.
Ninety percent of the human genome is not translated into protein and was once considered useless rubbish. It was later discovered that the genes in this area functioned in a mystical way, and these genes tended to work in tandem. The new method developed by Church et al. Targets and activates these poorly understood DNA dark substances.