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Acclaim Mixed-Mode HILIC-1 LC Column

Reversed-Phase and Hydrophilic Interaction Phases Combined on a Single Column

The Acclaim^? Mixed-Mode HILIC-1 column utilizes a unique silica-based, mixed-mode stationary phase that combines both reversed-phase (RP) and hydrophilic interaction liquid chromatography (HILIC) properties. The column functional group features a hydrophobic alkyl chain and hydrophilic diol functionality. This combination allows both hydrophobic interaction and hydrophilic interaction to be utilized to optimize separations.

Operates in both RP and HILIC modes
Retains highly polar molecules
Unique selectivity complementary to RP columns
Superior performance compared to conventional diol-based columns
High efficiency column for high resolution separations

The Acclaim Mixed-Mode HILIC-1 columns consist of 5 μm high-purity, porous, spherical silica with 120 ?-diameter pores bonded with proprietry functional groups, which provide unsurpassed resolution and peak symmetry for a variety of polar and nonpolar molecules.

Wide Range of Applications

The Acclaim Mixed-Mode HILIC-1 column separates both polar and nonpolar molecules with selectivity complementary to RP columns and is suitable for a broad range of applications, including drug metabolites, lipids, polyethylene glycols (PEGs), ethoxylated surfactants and more.

技術(shù)參數(shù)：

Acclaim Mixed-Mode HILIC-1 Columns Specifications
Particle size:	5 ?m
Base silica:	Spherical, high-purity
Pore size:	120 ?
Surface area:	300 m²/g
Column chemistry:	Proprietary alkyl diol

訂購信息：

Analytical Columns
Acclaim Mixed-Mode HILIC-1, 3?m Analytical (3.0 x 150mm)	070090
Acclaim Mixed-Mode HILIC-1, 3?m Analytical (3.0 x 50mm)	071912
Acclaim Mixed-Mode HILIC-1, 3?m Analytical (2.1 x 150mm)	070091
Acclaim Mixed-Mode HILIC-1, 5 ?m (4.6 x 150 mm)	066843
Acclaim Mixed-Mode HILIC-1, 5?m (4.6 x 250 mm)	066844
Acclaim Mixed-Mode HILIC-1, 5 ?m (2.1 x 150 mm)	066847

Guard Columns
Acclaim Mixed-Mode HILIC-1, 5 ?m Guard Cartrdiges, (4.6 x 10 mm), 2 ea (use V-2 Holder)	069706
Acclaim Mixed-Mode HILIC-1, 5?m Guards (3 x 10mm), 2ea, requires holder 069580	071913
Acclaim Mixed-Mode HILIC-1, 5?m, Guards (2.1 x 10mm), 2 ea; requires holder 069580	069694
Acclaim SST Guard Cartridge Holder V-2	069580
Acclaim Guard Kit (Holder and coupler) V-2	069707
Guard to Analytical Column Coupler V-2	074188