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BPS Bioscience的蛋白酶篩選和檢測(cè)服務(wù)
- 公司名稱 BPS Bioscience Inc.
- 品牌 BPS Bioscience
- 型號(hào)
- 產(chǎn)地
- 廠商性質(zhì) 生產(chǎn)廠家
- 更新時(shí)間 2023/12/19 23:23:59
- 訪問(wèn)次數(shù) 251
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BPS Bioscience專注于開(kāi)發(fā)高質(zhì)量的產(chǎn)品，提供優(yōu)質(zhì)的客戶服務(wù)，并維護(hù)穩(wěn)健的質(zhì)量管理體系。BPS Bioscience現(xiàn)已通過(guò)ISO 9001:2015認(rèn)證，確保質(zhì)量的持續(xù)監(jiān)控和持續(xù)改進(jìn)，從而滿足客戶需求。
BPS Bioscience產(chǎn)品涉及臨床前藥物開(kāi)發(fā)過(guò)程的每個(gè)階段。其中部分產(chǎn)品可以用于許多研究階段。BPS Bioscience將繼續(xù)豐富我們的產(chǎn)品線，希望以此推動(dòng)了整個(gè)早期藥物研發(fā)過(guò)程。
生物試劑
- 提供商：
BPS Bioscience
- 服務(wù)名稱：
BPS Bioscience的蛋白酶篩選和檢測(cè)服務(wù)
Accelerate your drug discovery program with Protease Screening and Profiling Services from BPS Bioscience, Inc. Trust us to provide you with high quality data with fast turnaround time. Our team of experts along with our broad services portfolio makes it easy to:
Screen for inhibitors/targets using our panel of many different assays including Cathepsins, Caspases, Dipeptidyl Peptidases (DPPs), Deubiquitinases, and other Proteases
Select from IC50 determination and single point concentrations
Receive data within days of compound submission
Perform follow-up studies using the same proteins manufactured in-house
Get questions answered or project guidance in a time-efficient manner
Biochemical Assays:
| Aspartic Proteases | Cysteine Proteases | Metalloproteases | Serine Proteases |
|---|---|---|---|
| BACE1 | SARS-CoV-1 3C-like Protease (3CL) | ADAM17 | CLP |
| Caspase-3 | SARS-CoV-2 3C-like Protease (3CL) | MMP1 | DPP3 |
| Caspase-6 | SARS-CoV-2 Papain-like Protease (PLPro) | MMP2 | DPP4 |
| Caspase-7 | A20 | MMP3 | DPP7 |
| Caspase-8 | Ataxin-3 | MMP7 | DPP8 |
| Caspase-9 | Cathepsin B | MMP8 | DPP9 |
| Renin, activated | Cathepsin F | MMP9 (Q279R) | FAP |
| Cathepsin L | MMP10 | Furin | |
| Cathepsin S | MMP11 | HCV1a (D168V) | |
| Cathepsin V | MMP12 | HCV1b | |
| MALT1 | MMP13 | HCV1b (D168V) | |
| OTUD6Bc | MMP14 | HCV1b (R155K) | |
| UCHL1 | HCV1b (R155Q) | ||
| UCHL3 | HCV2a | ||
| USP2 | POP | ||
| USP5 | Protein C, activated | ||
| USP7 | TMPRSS2 | ||
| USP8 | |||
| USP10 | |||
| USP14 |
Note: Not all targets will have a commercially available reference control. Please inquire with our team if you need to furnish your own controls for specific targets.
Protease signaling pathways regulate a wide range of vital physiological processes, including digestion of food, lysosome and proteasome degradation, apoptosis, blood coagulation, and cell cycle regulation.
The dysregulation of protease activity can lead to pathologies such as arthritis and inflammatory diseases,cardiovascular disorders, cancer, osteoporosis, Alzheimer’s, and other neurological disorders. Several small molecule, protease inhibitor drugs are already on the market and many more are in development.
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