CBP60380 MCF-7人乳腺癌細胞
- 公司名稱 南京康佰生物科技有限公司
- 品牌 cobioer/科佰生物
- 型號 CBP60380
- 產(chǎn)地
- 廠商性質 生產(chǎn)廠家
- 更新時間 2021/9/15 9:16:34
- 訪問次數(shù) 3521
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| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | T-25 Flask |
|---|---|---|---|
| 貨號 | CBP60380 | 應用領域 | 生物產(chǎn)業(yè) |
| 主要用途 | 僅限科研使用 |
CBP60380 |
|
I. General information
Synonyms: | MCF 7; MCF.7; MCF7; Michigan Cancer Foundation-7; ssMCF-7; ssMCF7; MCF7/WT; IBMF-7; MCF7-CTRL |
Background: | Established from the pleural effusion from a 69 year female caucasian suffering from a breast adenocarcinoma. Cells exhibit some features of differentiated mammary epithelium including oestradiol synthesis and formation of domes. Cells may carry B or C type retrovirus and are considered to represent a category 2 pathogen P2 containment. Cells express both the wild type and variant oestrogen receptors as well as progesterone receptor. The cells should be handled under laboratory containment level 2. |
Species: | Homo sapiens, human |
Tissue: | Mammary gland, breast; derived from metastatic site: pleural effusion |
Disease: | Breast adenocarcinoma |
Gender: | Female, 69 years |
Morphology: | Epithelial-like cells growing as monolayers |
Growth Mode: | Adherent |
Doubling Time: | ca. 50 hours range 30-72 hours |
DNA Profile: | Amelogenin: X Cobioer’s Cell Line Authentication Service |
Culture Medium: | MEM + 10% FBS+ 1% Non Essential Amino Acids NEAA + 1mM Sodium Pyruvate NaP+ 10 µg/ml human insulininsulinoptional |
Cryopreservation medium: | 90% FBS+10%DMSO |
Photo: |
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Antigen Expression: | Blood Type O; Rh+ |
Receptor Expression: | Estrogen receptor, expressed |
Genes Expressed: | Insulin-like growth factor binding proteins IGFBP BP-2; BP-4; BP-5 |
Immunology: | cytokeratin +, cytokeratin-7 -, cytokeratin-8 +, cytokeratin-17 -, cytokeratin-18 +, cytokeratin-19 +, desmin -, endothel -, EpCAM +, GFAP -, neurofilament -, vimentin - |
Molec. Genetics: | Expression of fusion gene BCAS4-BCAS3 confirmed by RT-PCR |
Viruses: | ELISA: reverse transcriptase negative; PCR: EBV -, HBV -, HCV -, HHV-8 -, HIV -, HTLV-I/II -, MLV -, SMRV - |
Comments: | The MCF7 line retains several characteristics of differentiated mammary epithelium including ability to process estradiol via cytoplasmic estrogen receptors and the capability of forming domes. The cells express the WNT7B oncogene. |
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