濾光片集成微流控芯片

這些模塊化微流控芯片設(shè)計(jì)用于各種類型過(guò)濾器和培養(yǎng)基貼片的可逆集成（需單獨(dú)訂購(gòu)）。該裝置由兩個(gè)PC（聚碳酸酯）塑料板組成，每個(gè)板上有四個(gè)用于可逆裝配的集成磁鐵和一個(gè)彈性PDMS薄膜，以確保良好的密封性。芯片上部的Luer連接器允許在實(shí)驗(yàn)期間進(jìn)行液體灌注和動(dòng)態(tài)流動(dòng)該組件易于使用，并且可以可逆地訪問(wèn)芯片中的濾波器和單元，以便進(jìn)行下游分析。

微流控芯片有三種配置：

a）帶兩個(gè)連接器芯片的過(guò)濾器集成，用于跨接應(yīng)用，如死端過(guò)濾或跨接灌注。

b）帶有三個(gè)連接器芯片的過(guò)濾器集成，用于反式或順式貼片應(yīng)用，如死端過(guò)濾、橫流過(guò)濾等。

c）帶有四個(gè)連接器芯片的過(guò)濾器集成，用于反式或順式貼片應(yīng)用，如死端過(guò)濾、橫流過(guò)濾或氣液界面細(xì)胞培養(yǎng)等。

當(dāng)過(guò)濾器或補(bǔ)片放置在兩個(gè)板之間時(shí)，四對(duì)磁鐵之間的力確保在8千帕的壓力下自動(dòng)裝配。后，標(biāo)準(zhǔn)的Luer連接器的上板允許一個(gè)容易的灌注。

為確保高流量壓力（高達(dá)100千帕）下良好的密封性，芯片可放置在手動(dòng)螺紋夾具中進(jìn)行組裝和快速操作。在動(dòng)態(tài)流動(dòng)條件下的實(shí)驗(yàn)結(jié)束時(shí)，可以通過(guò)拆開(kāi)夾鉗和微流控芯片來(lái)輕松移除過(guò)濾器或補(bǔ)片?？梢园凑沾随溄佑嗁?gòu)?qiáng)A鉗！

好處

模塊化芯片的可逆補(bǔ)丁集成

用芯片模制的無(wú)泄漏Luer接頭

高抗光透明材料

標(biāo)準(zhǔn)顯微鏡玻片尺寸

組裝三個(gè)組件以創(chuàng)建完整的微流控平臺(tái)：

微流控芯片

夾緊

微濾器

濾光片集成微流控芯片

These modular microfluidic chips were designed for reversible integration of various types of filters and culture patches (to be ordered separately). The setup consists in two plastic plates in PC (Polycarbonate), each having four integrated magnets for reversible assembly and an elastomeric PDMS thin film to ensure good sealing. The Luer Connectors in the upper part of the chip allow liquid perfusion and dynamic flow conditions during your experiments. The assembly is easy to use and with a reversible access to filter and cells in chip for downstream analysis.

The microfluidic chip is available in three configurations:

a) Filter integration with tow connectors chip for trans- patch application, such as dead-end filtration or trans patch perfusion.
b) Filter integration with three connectors chip for trans- or cis- patch application, such as dead-end filtration, cross-flow filtration, etc.
c) Filter integration with four connectors chip for trans- or cis- patch application, such as dead-end filtration, cross-flow filtration, or air/liquid-liquid interface cell culture, etc.

When a filter or patch is placed between the two plates, the force between the four pairs of magnets ensures auto-assembling at pressures up to 8 kPa. Finally, the standard Luer Connectors of the upper plate allow an easy perfusion.

To ensure good sealing with high flow pressures (up to 100 kPa), the chip can be placed in a hand screwed clamp for assembling and fast operation. At the end of your experiment in dynamic flow conditions, the filter or patch can be easily removed by dissembling the clamps and the microfluidic chip. A clamp can be ordered by following this link!

Benefits

• Reversible patch integration thanks to the modular chip
• Leak-free Luer Connection molded with the chip 
• Highly-resistant and optically clear material
• Standard microscope glass slide size

Assemble the three components to create a complete microfluidic platform:

• Microfluidic chip
• Clamp
• Microfilter