北京Peprotech*450-01現(xiàn)貨Recombinant Human beta-NGF*
參考價(jià) | ¥ 12 |
訂貨量 | ≥1 |
- 公司名稱 北京雅安達(dá)生物技術(shù)有限公司
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北京Peprotech*450-01現(xiàn)貨Recombinant Human beta-NGF*
品編號(hào):450-01
別名:NGF-β, beta-Nerve Growth Factor
北京Peprotech*450-01現(xiàn)貨Recombinant Human beta-NGF*
描述:β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. The functional form of Recombinant Human β-NGF is a non-covalently-linked homodimer of two 13.5 kDa, polypeptide monomers that each contain 120 amino acids and three disulfide bonds, which are required for biological activity.
氨基酸序列:SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA
來源:E.coli
純度:Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:determined by its ability to stimulate chick E9 DRG neurite outgrowth. The ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106units/mg.
交叉反應(yīng):Chicken, Hamster, Mouse, Rat, Human, Leech
研究領(lǐng)域:
血管生成/ 心血管 | 趨化 | ||
糖尿病/ 體重調(diào)節(jié) | 炎癥 | ||
神經(jīng)生物學(xué) | 干細(xì)胞及分化 | ||
創(chuàng)傷修復(fù) |
原產(chǎn)國:
USA