CellZscope 全自動細胞跨膜電阻測量儀
- 公司名稱 QUANTUM量子科學儀器貿(mào)易(北京)有限公司
- 品牌 其他品牌
- 型號 CellZscope
- 產(chǎn)地 anoAnalytics
- 廠商性質(zhì) 生產(chǎn)廠家
- 更新時間 2024/4/18 9:35:05
- 訪問次數(shù) 18675
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產(chǎn)地類別 | 進口 | 價格區(qū)間 | 面議 |
---|---|---|---|
應用領域 | 醫(yī)療衛(wèi)生,生物產(chǎn)業(yè) |
德國 Nanoanalytics
全自動細胞跨膜電阻測量儀
德國 NanoAnalytics公司推出的細胞跨膜電阻儀(即實時無標記細胞動態(tài)分析儀)——cellZscope是由電腦控制,全自動、長時間實時監(jiān)測細胞層生理學參數(shù)的儀器,可實時輸出跨膜電阻(TEER)重要指標,次監(jiān)測樣品6/24/48/72/96個。尤其適用于細胞屏障(消化道、呼吸道、血腦屏障)性,藥物轉(zhuǎn)運,納米藥物研發(fā),中樞神經(jīng)系統(tǒng)疾病,腫瘤等域的研究。 |
設備點
☆ 不干擾細胞正常生長環(huán)境--測量的數(shù)值更加真實
☆ 超長時間全自動實時分析--測量的數(shù)據(jù)更加完整
☆ 測量采用更寬的頻率范圍--擬合的數(shù)據(jù)更加準確
☆ 構建的數(shù)理模型更加細致--電生理參數(shù)更加豐富
☆ 可兼容多種類型培養(yǎng)插件--耗材選擇更加多樣化
技術原理
表皮或內(nèi)皮細胞之間通過緊密連接形成層具選擇性的細胞屏障,細胞屏障不僅控制鄰近細胞間間隙對各種溶解物的擴散滲透率,而且調(diào)控跨細胞物質(zhì)轉(zhuǎn)運。細胞屏障的存在方面保護了機體免受有害物質(zhì)的傷害,另方面也限制了治療性藥物的進入。
細胞屏障的通透性可以通過跨膜電阻(即TEER,Transepithelial resistance)來反映,細胞屏障的通透性與跨膜電阻TEER之間的關系為:通透性越高TEER越低,反之亦然。
基本參數(shù)
☆ 可以直接讀取細胞屏障層的電阻值TEER (Ω.cm2);
☆ *兼容常用廠家的Transwell細胞培養(yǎng)皿。包括BD,Biosciences,Corning,Bio-One,Millipore等。無儀器自帶耗材和其他額外耗材;
☆ 細胞模塊可以同時容納6/24/48/72/96個培養(yǎng)皿。每個培養(yǎng)皿都有三種型號可選:小孔型(“24孔”型Transwell培養(yǎng)皿),中孔型(“12孔”型Transwell培養(yǎng)皿),大孔型(“6孔”型Transwell培養(yǎng)皿);
☆ cellZscope細胞模塊是放置于標準的細胞培養(yǎng)箱中,實時動態(tài)監(jiān)測,可以監(jiān)測數(shù)秒到數(shù)周的細胞動態(tài)生物學行為變化。
應用域
cellZscope可應用于內(nèi)皮屏障相關的研究域:
☆ 細胞屏障(血腦屏障、鼻黏膜及消化道屏障等)的性
☆ 緊密連接動力學
☆ 新型藥物研發(fā)
☆ 藥物或毒物對細胞屏障功能的影響
☆ 腫瘤侵襲轉(zhuǎn)移
☆ 免疫細胞在中樞神經(jīng)系統(tǒng)疾病中的作用
設備型號
4種不同型號可供選擇:cellZscopeE、cellZscope+、cellZscope2、cellZscope3
cellZscopeE
☆ 入門的cellZscopeE型號更靈活,如果您沒有較高的通量檢測,可以選擇cellZscopeE
☆ 多達6個通道的TER檢測
☆ 細胞培養(yǎng)環(huán)境下實時長時間檢測
☆ 可以兼容多種transwell小室
☆ 操作簡單,清洗方便。
cellZscope+
☆ cellZscope+ 型號是德國nanoanalytics公司多年自動化細胞監(jiān)控設備開發(fā)經(jīng)驗的成果集中體現(xiàn)
☆ *和準確的阻抗結果讀取,全頻譜信息
☆ 大的靈活性,不同孔徑的細胞培養(yǎng)條件可供選擇
☆ 可持續(xù),易于使用和維護,不需殊工具,細胞模塊上、下部分均可滅菌
☆ cellZscope+型號設計保證了簡單的操作和大的靈活性。細胞模塊為研究人員提供了監(jiān)測所有孔的完整的頂部和基底外側(cè)信息。
cellZscope2
☆ cellZscope2型號為基于阻抗的細胞監(jiān)測提供了些全新的體驗
☆ 在時間分辨率達到了新的高性能基準。多通道數(shù)據(jù)采集使cellZscope2提供了較快、*的阻抗輸出
☆ 殊的易用性,更換培養(yǎng)基等細胞培養(yǎng)常規(guī)操作,無需插拔數(shù)據(jù)線,數(shù)據(jù)穩(wěn)定性更高
☆ cellZscope2更快的性能允許更高的吞吐量。在實驗前,實驗中和實驗后,方便細胞模塊與控制模塊的數(shù)據(jù)對接
cellZscope3
☆ 四個細胞模塊,每個有24個孔,可以連接到個cellZscope3控制器,同時測量96個孔
☆ 自動化的,快速的全程監(jiān)控,獲得數(shù)天或數(shù)周的長期監(jiān)測數(shù)據(jù)
☆ 殊的易用性,更換培養(yǎng)基等細胞培養(yǎng)常規(guī)操作,無需插拔數(shù)據(jù)線,數(shù)據(jù)穩(wěn)定性更高
☆ 時間分辨率高:cellZscope3每30秒完成單個細胞模塊即24孔的檢測
四種型號詳細比較
CellZscopeE | cellZscope+ | cellZscope2 | cellZscope3 | |
支持transwell小室尺寸 | 6-/12-/24-well | 6-/12-/24-well | 6-/12-/24-well | 6-/12-/24-well |
不同transwell小室尺寸組合 | √ | √ | √ | √ |
與標準transwell小室兼容性 | √ | √ | √ | √ |
細胞模塊部件可滅菌 | √ | √ | √ | √ |
測量速度 | 6孔全部完成約1min | 24孔全部完成約4min | 24孔全部完成約1..2min | 每24孔全部完成約30s |
細胞模塊底座 | 無 | 無 | √ | √ |
可讀取參數(shù) | TER/ Rmed | TER/Ccl/Rmed/Rins/ Cins/CPE_A/CPE_n | TER/Ccl/Rmed/Rins/ Cins/CPE_A/CPE_n | TER/Ccl/Rmed/Rins/ Cins/CPE_A/CPE_n |
細胞模塊well數(shù) | 6 | 24 | 24 | 96 |
6-well size | √ | √ | √ | √ |
12-well size | √ | √ | √ | √ |
24-well size | √ | √ | √ | √ |
應用案例
■ 用跨膜電阻(TEER)值法檢測Caco-2細胞屏障的完整性
用跨膜電阻(TEER)值法檢測Caco-2細胞屏障的完整性。Caco-2細胞以5×103細胞/孔的密度接種于Transwell小室中。前周每隔天更換次新鮮培養(yǎng)基,然后在接下來的兩周每天更換次新鮮培養(yǎng)基。并使用NanoAnalytics公司 Cellzscope2軟件對所得實時數(shù)據(jù)進行分析。
Caco-2細胞培養(yǎng)19天后,細胞跨膜電阻值≥500 Ω·cm2,細胞形成個完整的單層屏障,完整性通過Lucifer Yellow滲透性測試得到進步得到證實,進而單層細胞屏障可用于下步的運輸實驗。SRL和SRL NCs的細胞毒性呈濃度依賴性(圖1B)。SRL和SRL-NCs的半數(shù)大抑菌濃度分別為147.51μg/mL和165.41μg/mL。在50μg/mL的SRL和SRL-NCs作用72h后,細胞存活率保持在80%以上。這表明本研究中使用的SRL濃度不會引起顯著的細胞毒性。因此,藥物對細胞活力的影響可以忽略不計。
轉(zhuǎn)運實驗采用完整緊密連接的腸上皮Caco-2細胞單層作為模型,SRL和SRL-NCs組的跨膜電阻(TEER)值(圖1D)在整個轉(zhuǎn)運過程中未顯示出任何顯著變化,表明在沒有緊密連接遭到破壞的情況下,Caco-2細胞單層的完整性得以維持。
將含藥物HBSS緩沖液和空白HBSS緩沖液分別添加到模型頂層(AP)和基底外側(cè)(BL)側(cè),模擬藥物從GIT到血液的吸收和轉(zhuǎn)運途徑。也就是說,細胞層從GIT中運出藥物并將其輸送到血液/腸系膜淋巴。相反,當將藥物HBSS緩沖液添加到BL側(cè)和空白HBSS緩沖液添加到AP側(cè)時,模擬了動物血液進入腸腔的過程。計算出SRL-NCs的流出速率由于Papp、BL-AP/Papp、AP-BL與SRL顯著不同(圖1C)。原因可能是藥物被納米化后藥物變得更小,比表面積增加,因此跨單層的轉(zhuǎn)運顯著增強。另種可能是細胞占據(jù)了整個SRL-NCs結構,因此與SRL組相比,通透性增強,SRL-NCs組AP→BL側(cè)Papp高5.6倍,外排率低。
圖1 SRL和SRL-NCs在Caco-2細胞單層屏障的轉(zhuǎn)運。(A)跨膜轉(zhuǎn)運實驗示意圖;(B)不同濃度SRL和SRL-NCs對Caco-2細胞活力的影響(n=6)。(C)SRL和SRL-NCs-Papp、A-B、Papp、B-A和Caco-2細胞單層的流出比(n=*6,*P<0.01)。(D)Caco-2細胞單層TEER值在整個轉(zhuǎn)運過程中的變化。數(shù)據(jù)表示為平均標準差。
數(shù)據(jù)測試
1.細胞屏障的性
cellZscope可以連續(xù)監(jiān)測細胞幾天甚至幾星期的生理狀態(tài)。從cellZscope所提供的跨膜電阻值(TEER)和電容值(Ccl)這兩個參數(shù)可以獲知當前的細胞狀態(tài),包括融合度和分化度。CaCO2是源自人類結腸癌細胞系,通常用于藥物轉(zhuǎn)運研究,圖中cellZscope跟蹤記錄了CaCO2細胞層的形成和分化的信息,自動化的記錄了從接種細胞開始并持續(xù)觀察21天。
長時間監(jiān)測細胞屏障的形成
2.緊密連接動力學
上皮細胞和內(nèi)皮細胞的跨膜阻抗值與細胞間緊密連接密切相關。緊密連接可影響細胞間物質(zhì)轉(zhuǎn)運過程。通過cellZscope測量細胞層跨膜電阻可以用于研究緊密連接動力學。圖示MDCK細胞對不同濃度的EGTA的反應。
細胞緊密動力學研究
3.新型藥物研發(fā)
4.藥物或毒物對細胞屏障功能的影響
5.腫瘤侵襲轉(zhuǎn)移
6.免疫細胞在中樞神經(jīng)系統(tǒng)疾病中的作用
發(fā)表文章
2021
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2020
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M. Heslera, D.H.Schwarz, S. Dähnhardt-Pfeiffer, S. Wagner, H. von Briesen, G. Wenz, Y. Kohl
Eur. J. Pharm. Sci. 143, 105181 (2020). → doi: 10.1016/j.ejps.2019.105181
4. Serine proteases as luminal mediators of intestinal barrier dysfunction and symptom severity in IBS
S. Edogawa, A. Ledwinson, S.A. Peters, L.L. Chikkamenahalli, W. Sundt, S. Graves, S.V. Gurunathan, M. Breen-Lyles, S. Johnson, R. Dyer, R. Graham, J. Chen, P. Kashyap, G. Farrugia, M. Grover. Gut 69, 62 (2020). → doi: 10.1136/gutjnl-2018-317416
5. TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function
G. Merlen, N. Kahale, J. Ursic-Bedoya, V. Bidault-Jourdainne, H. Simerabet, I. Doignon, Z. Tanfin, I. Garcin, N. Péan, J. Gautherot, A. Davit-Spraul, C. Guettier, L. Humbert, D. Rainteau, K. Ebnet, Ch. Ullmer, D. Cassio, T. Tordjmann. Gut 69, 146 (2020). → doi: 10.1136/gutjnl-2018-31697
6. Enteropathogenic Escherichia coli (EPEC) Recruitment of PAR Polarity Protein Atypical PKC? to Pedestals and Cell–Cell Contacts Precedes Disruption of Tight Junctions in Intestinal Epithelial Cells
R. Tapia, S.E. Kralicek, G.A. Hecht Int. J. Mol. Sci. 21, 527 (2020). → doi: 10.3390/ijms21020527
7. Meprin ß: A novel regulator of blood–brain barrier integrity
M. Gindorf, S.E. Storck, A. Ohler, F. Scharfenberg, Ch. Becker-Pauly, C.U. Pietrzik, J. Cereb. Blood Flow Metab. XX, YY (2020). → doi: 10.1177/0271678X20905206
8. Tight junctions in the blood–brain barrier promote edema formation and infarct size in stroke – Ambivalent effects of sealing proteins
L. Winkler, R. Blasig, O. Breitkreuz-Korff, Ph. Berndt, S. Dithmer, H.C. Helms, D. Puchkov, K. Devraj, M. Kaya, Z. Qin, S. Liebner, H. Wolburg, A.V. Andjelkovic, A. Rex, I.E. Blasig, R.F. Haseloff, J. Cereb. Blood Flow Metab. XX, YY (2020). → doi: 10.1177/0271678X20904687
9. Identification of Parthenolide Dimers as Activators of Pyruvate Kinase M2 in Xenografts of Glioblastoma Multiforme in Vivo
Y. Ding, Q. Xue, S. Liu, K. Hu, D. Wang, T. Wang, Y. Li, H. Guo, X. Hao, W. Ge, Y. Zhang, A. Li J. Li, Y. Chen, Q. Zhang, J. Med. Chem. XX, YY (2020). → doi: 10.1021/acs.jmedchem.9b01328
10. Monophosphoryl Lipid a Attenuates Multiorgan Dysfunction During Post-Burn Pseudomonas Aeruginosa Pneumonia in Sheep
S. Fukuda, K. Ihara, J.K. Bohannon, A. Hernandez, N.K. Patil, L. Luan, C. Stothers, R. Stark, D.S. Prough, D.N. Herndon, E.R. Sherwood, P. Enkhbaatar, Shock 53, 307 (2020). → doi: 10.1097/SHK.0000000000001364
11. Claudin-12 deficiency causes nerve barrier breakdown, mechanical hypersensitivity and painfulness in polyneuropathy
J.T.-C. Chen, X. Hu, K. Doppler, O. Breitkreuz-Korff, I.U.C. Otto, J. Schwabe, A.-K. Reinhold, D. Günzel, S. Dithmer, M.K. Hankir, P. Fallier-Becker, L. Winkler, R. Blasig, C. Sommer, A. Brack, I.E. Blasig, H.L. Rittner. XX, YY (2020). → doi: 10.1101/768267
2019
1. Enhanced Bioavailability by Orally Administered Sirolimus Nanocrystals
J. Kong, K. Wu, Y. Ji, K. Chen, J. Zhang, H. Sun, Y. Liang, W. Liang, Y. Chang, J. Cheng, J. Tong, J. Li, G. Xing, G. Chen. ACS Appl. Bio Mater. 2, 4612 (2019). → doi: 10.1021/acsabm.9b00695
2. Effect of E Cigarette Emissions on Tracheal Cells Monitored at the Air–Liquid Interface Using an Organic Electrochemical Transistor
M.P. Ferro, L. Leclerc, M. Sleiman, B. Marchiori, J. Pourchez, R.M. Owens, M. Ramuz
Adv. Biosys. 3, 1800249 (2019). → doi: 10.1002/adbi.201800249
3. Oxidative Stress Increases Endogenous Complement-Dependent Inflammatory and Angiogenic Responses in Retinal Pigment Epithelial Cells Independently of Exogenous Complement Sources
T.-O. Trakkides, N. Schäfer, M. Reichenthaler, K. Kühn, R.J.M.G.E. Brandwijk, E.J.M. Toonen, F. Urban, J. Wegener, V. Enzmann, D. Pauly
Antioxidants 8, 548 (2019). → doi: 10.3390/antiox8110548
4. Non-pooled Human Platelet Lysate: A Potential Serum Alternative for In Vitro Cell Culture
M. Hesler, Y. Kohl, S. Wagner, H. von Briesen
ATLA, Altern. Lab. Anim. 47, 116 (2019). → doi: 10.1177/0261192919882516
5. Differential modulation of transendothelial electrical resistance by TRPV4 agonists is mediated by apoptosis and/or necrosis
N. Pairet , S. Mang, T. Kiechle, N. Laufhäger, P. Dietl, D.J. Lamb
Biochem. Biophys. Rep. 20, 100672 (2019). → doi: 10.1016/j.bbrep.2019.100672
6. Targeting claudin-4 enhances chemosensitivity of pancreatic ductal carcinomas
T. Sasaki, R. Fujiwara-Tani, S. Kishi, S. Mori, Y. Luo, H. Ohmori, I. Kawahara, K. Goto, Y. Nishiguchi, T. Mori, M. Sho, M. Kondo, H. Kuniyasu
Cancer Med. 8, 6700 (2019). → doi: 10.1002/cam4.2547
7. Toll-like receptor 3-mediated inflammation by p38 is enhanced by endothelial nitric oxide synthase knockdown
S.R. Koch, H. Choi, E.H. Mace, R.J. Stark
Cell Commun. Signaling 17, 33 (2019). → doi: 10.1186/s12964-019-0345-3
8. Stimulation of the A2B Adenosine Receptor Subtype Enhances Connexin26 Hemichannel Activity in Small Airway Epithelial Cells
A. Dierksa, A. Badera, T. Lehricha, A. Ngezahayo
Cell. Physiol. Biochem. 53, 606 (2019). → doi: 10.33594/000000160
9. Endothelial tight junctions and their regulatory signaling pathway
X. Cong, W. Kong
Cell. Signalling 66, 109485 (2019). → doi: 10.1016/j.cellsig.2019.109485
10. Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability
J. Miranda, D. Martín-Tapia, Y. Valdespino-Vázquez, L. Alarcón, A. Espejel-Nuñez, M. Guzmán-Huerta, J.E. Muñoz-Medina, M. Shibayama, B. Chávez-Munguía, G. Estrada-Gutiérrez, S. Lievano, J.E. Ludert, L. González-Mariscal
Cells 8, 1174 (2019). → doi: 10.3390/cells8101174
11. Transient blood–brain barrier disruption isinduced by low pulsed electrical fields in vitro: ananalysis of permeability and trans-endothelialelectric resistivity
S. Sharabi, Y. Bresler, O. Ravid, Ch. Shemesh, D. Atrakchi, M. Schnaider-Beeri, F. Gosselet, L. Dehouck, D. Last, D. Guez, D. Daniels, Y. Mardor, I. Cooper
Drug Delivery 26, 459 (2019). → doi: 10.1080/10717544.2019.1571123
12. In vitro and in vivo effects of a mycotoxin, deoxynivalenol, and a trace metal, cadmium, alone or in a mixture on the intestinal barrier
S. Luo, Ch. Terciolo, A.P.F.L. Bracarense, D. Payros, Ph. Pinton, I.P. Oswald
Environ. Int. 132, 105082 (2019). → doi: 10.1016/j.envint.2019.105082
13. A unified in vitro test system for the assessment of tight junction modulators
D. Saaber, S. Reichl
Eur. J. Pharm. Biopharm. 142, 353 (2019). → doi: 10.1016/j.ejpb.2019.07.004
14. The impact of gastrointestinal mucus on nanoparticle penetration – in vitro evaluation of mucus-penetrating nanoparticles for photodynamic therapy
L. Mahlert, J. Anderski, D. Mulac, K. Langer
Eur. J. Pharm. Sci. 133, 28 (2019). → doi: 10.1016/j.ejps.2019.03.010
15. Revisiting an old antibiotic: bacitracin neutralizes binary bacterial toxins and protects cells from intoxication
L. Schnell, I. Felix, B. Müller, M. Sadi, F. von Bank, P. Papatheodorou, M.R. Popoff, K. Aktories, E. Waltenberger, R. Benz, C. Weichbrodt, M. Fauler, M. Frick, H. Barth
FASEB J. 33, 5755 (2019). → doi: 10.1096/fj.201802453R
16. Impedance Spectroscopy as a Tool for Monitoring Performance in 3D Models of Epithelial Tissues
T. Gerasimenko, S. Nikulin, G. Zakharova, A. Poloznikov, V. Petrov, A. Baranova, A. Tonevitsky
Front. Bioeng. Biotechnol. 7, 474 (2019). → doi: 10.3389/fbioe.2019.00474
17. PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation
I. Wimmer, S. Tietz, H. Nishihara, U. Deutsch, F. Sallusto, F. Gosselet, R. Lyck, W.A. Muller, H. Lassmann, B. Engelhardt
Front. Immunol. 10, 711 (2019). → doi: 10.3389/fimmu.2019.00711
18. Autophagy Protects the Blood-Brain Barrier Through Regulating the Dynamic of Claudin-5 in Short-Term Starvation
Z. Yang, Ch. Huang, Y. Wu, B. Chen, W. Zhang, J. Zhang
Front. Physiol. 10, 2 (2019). → doi: 10.3389/fphys.2019.00002
19. Structure and biological activities of a hexosamine-rich cell wall polysaccharide isolated from the probiotic Lactobacillus farciminis
E. Maes, I. Sadovskaya, M. Lévêque, E. Elass-Rochard, B. Payré, Th. Grard, V. Théodorou, Y. Guérardel, M. Mercier-Bonin
Glycoconjugate J. 36, 39 (2019). → doi: 10.1007/s10719-018-09854-y
20. IL-13 Impairs Tight Junctions in Airway Epithelia
H. Schmidt, P. Braubach, C. Schilpp, R. Lochbaum, K. Neuland, K. Thompson, D. Jonigk, M. Frick, P. Dietl, O.H. Wittekindt
Int. J. Mol. Sci. 20, 3222 (2019). → doi: 10.3390/ijms20133222
21. Temporal Effects of Quercetin on Tight Junction Barrier Properties and Claudin Expression and Localization in MDCK II Cells
E. Gamero-Estevez, S. Andonian, B. Jean-Claude, I. Gupta, A.K. Ryan
Int. J. Mol. Sci. 20, 4889 (2019). → doi: 10.3390/ijms20194889
22. The Influence of Capsaicin on the Integrity of Microvascular Endothelial Cell Monolayers
M. Kaiser, M. Burek, S. Britz, F. Lankamp, S. Ketelhut, B. Kemper, C. Förster, Ch. Gorzelanny, F.M. Goycoolea
Int. J. Mol. Sci. 20, 122 (2019). → doi: 10.3390/ijms20010122
23. Controversial roles for dexamethasone in glioblastoma – Opportunities for novel vascular targeting therapies
D. Dubinski, E. Hattingen, Ch. Senft, V. Seifert, K.G. Peters, Y. Reiss, K. Devraj, K.H. Plate
J. Cereb. Blood Flow Metab. 39, 1460 (2019). → doi: 10.1177/0271678X19859847
24. Short communication: Processed bovine colostrum milk protein concentrate increases epithelial barrier integrity of Caco-2 cell layers
R.C. Anderson, J.E. Dalziel, N.W. Haggarty, K.E. Dunstan, P.K. Gopal, N.C. Roy
J. Dairy Sci. 102, 10772 (2019). → doi: 10.3168/jds.2019-16951
25. Impact of Docetaxel on blood-brain barrier function and formation of breast cancer brain metastases
S. Bernatz, E.I. Ilina, K. Devraj, P.N. Harter, K. Mueller, S. Kleber, Y. Braun, C. Penski, Ch. Renner, R. Halder, L. Jennewein, Ch. Solbach, F. Thorsen, B.C. Pestalozzi, A. Mischo, M. Mittelbronn
J. Exp. Clin. Cancer Res. 38, 434 (2019). → doi: 10.1186/s13046-019-1427-1
26. Fucosyltransferase 4 and 7 mediates adhesion of non-small cell lung cancer cells to brain-derived endothelial cells and results in modification of the blood–brain-barrier: in vitro investigation of CD15 and CD15s in lung-to-brain metastasis
S.A. Jassam, Z. Maherally, K. Ashkan, G.J. Pilkington, H.L. Fillmore
J. Neuro-Oncol. 143, 405 (2019). → doi: 0.1007/s11060-019-03188-x
27. Haem iron reshapes colonic luminal environment: impact on mucosal homeostasis and microbiome through aldehyde formation
O.C.B. Martin, M. Olier, S. Ellero-Simatos, N. Naud, J. Dupuy, L. Huc, S. Taché, V. Graillot, M. Levêque, V. Bézirard, C. Héliès-Toussaint, F.B.Y. Estrada, V. Tondereau, Y. Lippi, C. Naylies, L. Peyriga, C. Canlet, A.M. Davila, F. Blachier, L. Ferrier, E. Boutet-Robinet, F. Guéraud, V. Théodorou, F.H.F. Pierre
Microbiome 7, 72 (2019). → doi: 10.1186/s40168-019-0685-7
28. Improved Drug Delivery to Brain Metastases by Peptide-Mediated Permeabilization of the Blood–Brain Barrier
S.N. Aasen, H. Espedal, Ch.F. Holte, O. Keunen, T.V. Karlsen, O. Tenstad, Z. Maherally, H. Miletic, T. Hoang, A.V. Eikeland, H. Baghirov, D.E. Olberg, G.J. Pilkington, G. Sarkar, R.B. Jenkins, T. Sundstrøm, R. Bjerkvig, F. Thorsen
Mol. Cancer Ther. 18, 2171 (2019). → doi: 10.1158/1535-7163.MCT-19-0160
29. LRP1 Has a Predominant Role in Production over Clearance of Aß in a Mouse Model of Alzheimer’s Disease
B. Van Gool, S.E. Storck, S.M. Reekmans, B. Lechat, Ph.L.S.M. Gordts, L. Pradier, C.U. Pietrzik, A.J.M. Roebroek
Mol. Neurobiol. 56, 7234 (2019). → doi: 10.1007/s12035-019-1594-2
30. Side-directed Transfer and Presystemic Metabolism of Selenoneine in a Human Intestinal Barrier Model
I. Rohn, N. Kroepfl, J. Bornhorst, D. Kuehnelt, T. Schwerdtle
Mol. Nutr. Food Res. 63, 1900080 (2019). → doi: 10.1002/mnfr.201900080
31. Polyphenol Extracts from Three Colombian Passifloras (Passion Fruits) Prevent Inflammation-Induced Barrier Dysfunction of Caco-2 Cells
J.C. Carmona-Hernandez, G. Taborda-Ocampo, J.C. Valdez, B.W. Bolling, C.H. González-Correa
Molecules 24, 4614 (2019). → doi: 10.3390/molecules24244614
32. Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology
J.K. Sonner, M. Keil, M. Falk-Paulsen, N. Mishra, A. Rehman, M. Kramer, K. Deumelandt, J. Röwe, K. Sanghvi, L. Wolf, A. von Landenberg, H. Wolff, R. Bharti, I. Oezen, T.V. Lanz, F. Wanke, Y. Tang, I. Brandao, S.R. Mohapatra, L. Epping, A. Grill, R. Röth, B. Niesler, S.G. Meuth, Ch.A. Opitz, J.G. Okun Ch. Reinhardt, F.C. Kurschus, W. Wick, H.B. Bode, Ph. Rosenstiel, M. Platten
Nat. Commun. 10, 4877 (2019). → doi: 10.1038/s41467-019-12776-4
33. Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
L.-P. Wu, D. Ahmadvand, J. Su, A. Hall, X. Tan, Z.S. Farhangrazi, S.M. Moghimi
Nat. Commun. 10, 4635 (2019). → doi: 10.1038/s41467-019-12554-2
34. Targeting claudin-4 enhances CDDP-chemosensitivity in gastric cancer
Y. Nishiguchi, R. Fujiwara-Tani, T. Sasaki, Y. Luo, H. Ohmori, S. Kishi, S. Mori, K. Goto, W. Yasui, M. Sho, H. Kuniyasu
Oncotarget 10, 2189 (2019). → doi: 10.18632/oncotarget.26758
35. Corticosteroid signaling at the brain-immune interface impedes coping with severe psychological stress
A. Kertser, K. Baruch, A. Deczkowska, A. Weiner, T. Croese, M. Kenigsbuch, I. Cooper, M. Tsoory, S. Ben-Hamo, I. Amit, M. Schwartz
Sci. Adv. 5, eaav4111 (2019). → doi: 10.1126/sciadv.aav4111
36. Claudin-3-deficient C57BL/6J mice display intact brain barriers
M.C. Dias, C. Coisne, I. Lazarevic, P. Baden, M. Hata, N. Iwamoto, D.M.F. Francisco, M. Vanlandewijck, L. He, F.A. Baier, D. Stroka, R. Bruggmann, R. Lyck, G. Enzmann, U. Deutsch, Ch. Betsholtz, M. Furuse, S. Tsukita & B. Engelhardt
Sci. Rep. 9, 203 (2019). → doi: 10.1038/s41598-018-36731-3
37. Unraveling In Vivo Brain Transport of Protein-Coated Fluorescent Nanodiamonds
P. Moscariello, M. Raabe, W. Liu, S. Bernhardt, H. Qi, U. Kaiser, Y. Wu, T. Weil, H.J. Luhmann, J. Hedrich
Small 15, 1902992 (2019). → doi: 10.1002/smll.201902992
38. The Antibiotic Bacitracin Protects Human Intestinal Epithelial Cells and Stem Cell-Derived Intestinal Organoids from Clostridium difficile Toxin TcdB
Z. Zhu, L. Schnell, B. Müller, M. Müller, P. Papatheodorou, H. Barth
Stem Cells Int. 2019, 4149762 (2019). → doi: 10.1155/2019/4149762
39. Multi-endpoint toxicological assessment of polystyrene nano- and microparticles in different biological models in vitro
M. Heslera, L. Aengenheister, B. Ellinger, R. Drexel, S. Straskraba, C. Jost, S. Wagner, F. Meier, H. von Briesen, C. Büchel, P. Wick, T. Buerki-Thurnherr, Y. Kohl
Toxicol. In Vitro 61, 104610 (2019). → doi: 10.1016/j.tiv.2019.104610
40. Modelling Macular Edema: The Effect of IL-6 and IL-6R Blockade on Human Blood–Retinal Barrier Integrity In Vitro
M. Mesquida, F. Drawnel, P.J. Lait, D.A. Copland, M.L. Stimpson, V. Lloren, M.S. de la Maza, A. Adan, G. Widmer, P. Strassburger, S. Fauser, A.D. Dick, R.W. J. Lee, B. Molins
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2018
1. Brain Delivery of Multifunctional Dendrimer Protein Bioconjugates. Adv. Sci. (2018).
2. Importance of the IL-1 Axis in Haemophilus influenzae–stimulated M1 Macrophages Driving Transepithelial Signaling. Am. J. Respir. Cell Mol. Biol. (2018).
3. Effects of arsenolipids on in vitro blood-brain barrier model. Arch. Toxicol. (2018).
4. Reversible opening of the blood-brain barrier by claudin-5-binding variants of Clostridium perfringens enterotoxin's claudin-binding domain. Biomaterials. (2018).
5. HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model. EBioMedicine. (2018).
6. Real-time acquisition of transendothelial electrical resistance in an all-human, in vitro, 3-dimensional, blood–brain barrier model exemplifies tight-junction integrity. FASEB J. (2018)
7. Alteration of sphingolipid metabolism as a putative mechanism underlying LPS-induced BBB disruption. J. Neurochem. (2018).
8. A novel human induced pluripotent stem cell blood-brain barrier model: Applicability to study antibody-triggered receptor-mediated transcytosis. Sci. Rep. (2018).
9. Optimized procedures for generating an enhanced, near physiological 2D culture system from porcine intestinal organoids. Stem Cell Res. (2018).
10. Localized delivery of curcumin into brain with polysorbate 80-modified cerasomes by ultrasound-targeted microbubble destruction for improved Parkinson's disease therapy. Theranostics. (2018).
2017
1. Insights from mathematical modelling for T cell migration into the central nervous system. Math. Med. Biol. (2017)
2. Establishment of a method for evaluating endothelial cell injury by TNF-α in vitro for clarifying the pathophysiology of virus-associated acute encephalopathy. Pediatr. Res. (2017)
3. Development of Blood-Brain Barrier Permeable Nanoparticles as Potential Carriers for Salvianolic Acid B to CNS. Planta Med. (2017)
4. Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells. Stem Cell Rep. (2017)
5. Exfoliated graphene nanosheets: pH-sensitive drug carrier and anti-cancer activity. J. Colloid Interface Sci. (2017)
6. Endothelial Basement Membrane Laminin 511 Contributes to Endothelial Junctional Tightness and Thereby Inhibits Leukocyte Transmigration. Cell Rep. (2017)
7. Dual role of ALCAM in neuroinflammation and blood–brain barrier homeostasis. PNAS .(2017)
8. Gb3-binding lectins as potential carriers for transcellular drug delivery. Drug Delivery. (2017)
9. Early-lactation, but not mid-lactation, bovine lactoferrin preparation increases epithelial barrier integrity of Caco-2 cell layers. J. Dairy Sci. (2017)
10. Primary porcine brain endothelial cells as in vitro model to study effects of ultrasound on blood-brain barrier function. IEEE Trans. Sonics Ultrason. (2017)
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*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
用戶單位
部分國內(nèi)用戶:
廣東醫(yī)學院(湛江) | 天壇醫(yī)院 |
中國食品發(fā)酵研究院 | 醫(yī)科院藥植所 |
中科院高能物理研究所 | 上海市疾控中心 |
都師范大學 | 上海市第十人民醫(yī)院 |
都醫(yī)科大學-1 | 廣州市血液中心 |
深圳進技術研究院 | |
都醫(yī)科大學-2 | 浙江省醫(yī)藥學院 |
都醫(yī)科大學-3 | 山東省農(nóng)科院 |
GSK上海研發(fā)部 | 成都市第三人民醫(yī)院 |
都醫(yī)科大學-4 | 空軍軍醫(yī)大學附屬口腔醫(yī)院 |
南開大學 |